The AJMC® Heart Failure compendium is a comprehensive resource for clinical news and expert insights for the chronic condition in which the heart doesn't pump enough blood due to damaged heart muscle.
Midodrine Use Linked to Decrease in HFrEF-Related ED Visits
March 23rd 2024However, researchers saw higher risks of respiratory failure, longer stays in the intensive care unit, increased hospitalizations, and elevated mortality rates in patients with heart failure with reduced ejection fraction (HFrEF) taking the antihypotensive medication.
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Severe Prenatal Grief May Increase Child’s Heart Failure Risk
March 12th 2024Research found that maternal loss of a partner or older child, as well as the loss of a close relative due to unnatural causes in the year before or during pregnancy, were linked to a heightened risk of heart failure in offspring.
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30-Day Atorvastatin Improved Brachial Artery FMD in Patients With HFpEF, but More Research Is Needed
February 23rd 2024This study was the first of its kind to explore how taking statin medication affects blood vessel function and exercise response in patients with heart failure with preserved ejection fraction (HFpEF), although the cohort only included 16 patients.
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There Is No Interaction Between BMI and SGLT2 Inhibitor Efficacy in HF, Review Finds
February 23rd 2024Among patients with heart failure (HF), those taking dapaglifozin or empaglifozin had a 30% odds reduction in HF hospitalization, 14% odds reduction in cardiovascular mortality, and a 10% odds reduction in all-cause mortality compared with patients taking placebo.
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Permanent Pacemaker Implantation Frequently Follows Tricuspid Valve Surgery, Study Finds
February 5th 2024Among Medicare beneficiaries, implantation was especially frequent for female patients and those undergoing tricuspid valve replacement with or without concomitant left-sided heart surgeries.
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Low Muscle Mass, Hypoalbuminemia Increase Mortality Risk in ADHF
January 28th 2024Patients admitted to the hospital with acute decompensated heart failure (ADHF) who also had low muscle mass and hypoalbuminemia experienced a heightened mortality risk, suggesting skeletal muscle mass and serum albumin are important prognostic factors.
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Female Patients Less Likely to Receive Guideline-Directed HFrEF Therapies vs Males
January 25th 2024A recent study found that use of optimal guideline-directed medical therapies after heart failure with reduced ejection fraction (HFrEF) diagnosis is low overall, but especially among female patients compared with male patients.
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Similar Risk of Death Between Patients With HFimpEF, LVEF Above 40% in DELIVER Trial
January 24th 2024An analysis of the DELIVER trial also revealed an association between dapagliflozin treatment and reduced risk of cardiovascular death among individuals with heart failure with improved ejection fraction (HFimpEF).
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Patients With HFrEF, HFpEF See Different Functional Capacity Benefits With Dapagliflozin
December 7th 2023The DETERMINE-Reduced and DETERMINE-Preserved trials demonstrated varying benefits of dapagliflozin on Kansas City Cardiomyopathy Questionnaire Total Symptom Score and Physical Limitation Scale as well as 6-minute walk distance.
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Study: SGLT2is Should Be Continued Despite Initial eGFR Decline in Patients With HFmrEF/HFpEF
December 6th 2023Despite an initial drop in estimated glomerular filtration rate (eGFR) after 1 month of dapagliflozin, researchers say this is not associated with subsequent risk of cardiovascular or kidney events for patients with heart failure with mildly reduced ejection fraction (HFmrEF) or preserved ejection fraction (HFpEF).
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Benefits of Excluding Aspirin From Antithrombotic Regimen in Patients With LVADs
November 15th 2023New research highlighted how aspirin is unnecessary in antithrombotic regimens for patients with advanced heart failure and fully magnetically levitated left ventricular assist devices (LVADs).
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The weight loss drug semaglutide showed significant cardiovascular benefits; Texas and Florida are restricting the promotion of COVID-19 vaccines; some Ohio legislators are seeking to block courts from interpreting the state’s recently passed constitutional amendment that created a right to abortion.
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What We’re Reading: AI Heart Attack Detection; FDA Menthol Ban; Shooting Survivor Care Obstacles
November 7th 2023Artificial intelligence (AI) could help detect heart attack risk signs and prevent sudden cardiac death; Advocates demand the Biden administration finalize the proposed FDA ban on menthol cigarettes; Gun violence survivors and their families have many ongoing medical needs.
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Sacubitril/Valsartan Reduces Natriuretic Peptide Levels, Improves QOL in Patients With HFpEF
October 26th 2023The improvement in quality of life (QOL) seen with use of sacubitril/valsartan for heart failure with preserved ejection fraction (HFpEF) could potentially result in more favorable clinical results.
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GALACTIC Trial Reveals Less Successful RAAS Inhibitor Uptitration in Women Than Men
October 24th 2023Uptitration of renin-angiotensin-aldosterone system (RAAS) inhibitors was less successful in women than men with acute heart failure (AHF), especially in those with HF with reduced ejection fraction.
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BNP Levels May Not Be Effective Prognostic Tool for Patients With Cardiogenic Shock Using VADs
September 22nd 2023While B-type natriuretic peptide (BNP) levels remain high in patients with end-stage heart failure with cardiogenic shock, these levels lose their prognostic value in patients using ventricular assist devices (VADs).
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Tailored EHR Alerts Fail to Improve Acute HF Medication Prescription at Discharge
September 21st 2023A tailored electronic health record (EHR) alert system did not significantly increase the prescription of guideline-directed medical therapies (GDMT) at hospital discharge for patients with acute heart failure (AHF).
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Disparities in SDOH Highlight Need for Social Intervention in the HF Space
August 22nd 2023Data from the 1999-2018 National Health and Nutrition Examination Survey were used to analyze the prevalence of social determinants of health (SDOH) among patients with self-reported heart failure (HF).
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